Margins in the pharma supply chain

Who takes what, from the manufacturer down to the chemist.

Last checked 20 September 2026

A medicine’s MRP is divided between the manufacturer, sometimes a C&F agent, the stockist and the retailer. Commonly cited trade margins are around 10% for the stockist and 20% for the retailer, but they vary widely by product type, and schemes and discounts move the real figure a long way from the printed one.

The chain

StageRoleTypically earns
ManufacturerMakes the product, sets MRP within any price controlWhat is left after trade margins and its own costs
C&F agentHolds stock for the company in a state; usually does not buy itA commission, not a trade margin
Stockist / distributorBuys at PTS, sells to retailers at PTR, carries the credit riskAround 10%
Retailer / chemistBuys at PTR, sells at MRPAround 20%

A C&F agent is not a stockist

A carrying-and-forwarding agent holds the company’s stock on consignment and earns commission. A stockist buys the goods, owns them, and takes both the working-capital cost and the risk. Different economics entirely.

Why the headline margin is not the real one

A stockist working on "10%" is not making 10%. Take a line with a PTS of ₹82.29 and a PTR of ₹91.43 — ₹9.14 a pack, on paper. Then:

Then subtractEffect
Cash discount given to retailersDirectly off the ₹9.14
Breakage, damage and expiryA percentage of stock that earns nothing
Credit given, typically 30–60 daysA financing cost on every pack
Delivery and handlingReal cost of getting it to the chemist
Bad debtsOccasional, and painful when it happens

And add back the one that helps:

  • Free goods on a scheme. 10 + 1 means eleven saleable packs for the cost of ten, which is a real improvement in cost per unit and often the difference between a viable line and a pointless one.

Where distributors actually make money

  • Volume on fast movers, where a thin margin turns many times a year. See stock turnover.
  • Schemes, bought well and passed on selectively rather than automatically.
  • Not losing stock to expiry — the fastest available margin improvement in the trade, because it costs nothing but discipline. See batch tracking and FEFO.
  • Collecting on time. A margin you never collect is not a margin.
Margin & Markup Calculator — free, no signupMargin, markup and the selling price for a target margin, GST-aware.

What to watch, monthly

NumberWhy it matters
Gross margin by product groupAverages hide the lines that lose money
Value expiring within 90 daysThe last point at which you still have options
Days of outstanding receivablesMargin sitting in someone else’s shop
Stock turnoverHow hard your working capital is working
Are trade margins fixed by law?

Not generally. Price control operates on ceiling prices for scheduled formulations and on price increases for others, rather than by mandating a trade margin, though margin caps have applied to specific categories. Check the current position for what you handle.

Why do generics carry bigger margins?

Less brand pull means the trade has to be given a reason to stock and recommend them. The wider margin is that reason.

Should I take every scheme offered?

No. A scheme on a slow mover is dead stock with extra steps. Check the turnover of the line before committing capital to eleven packs of something that sells four a month.

Sources

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